Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene. CENPA is a histone H3 variant which is the critical factor determining the kinetochore position(s) on each chromosome in most eukaryotes including...
Centromere protein C is a protein that in humans is encoded by the CENPC gene (previously CENPC1). Centromere protein C is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper...
Centromere protein B also known as major centromere autoantigen B is an autoantigen protein of the cell nucleus. In humans, centromere protein B is encoded by the CENPB gene.
Centromere protein I is a protein that in humans is encoded by the CENPI gene.
Centromere protein N is a protein that in humans is encoded by the CENPN gene.
Centromere protein H is a protein that in humans is encoded by the CENPH gene. It is involved in the assembly of kinetochore proteins, mitotic progression and chromosome segregation.
Centromere protein O is a protein that in humans is encoded by the CENPO gene. CENPO is involved in cell proliferation and cell cycle progression and has been shown to be down-regulated in trisomic neurospheres a mouse model of Down Syndrome,...
Centromere protein F is a protein that in humans is encoded by the CENPF gene. It is involved in chromosome segregation during cell division. It also has a role in the orientation of microtubules to form cellular cilia.
The centromere links a pair of sister chromatids together during cell division. This constricted region of chromosome connects the sister chromatids, creating a short arm (p) and a long arm (q) on the chromatids. During mitosis, spindle fibers...
Centromere protein U is a protein that in humans is encoded by the CENPU gene. Centromere protein U is a factor that is needed for centromere assembly.